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Published: 08/08/2013 About provisions: The cesarean affects brain development Normal childbirth gi


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The normal vaginal childbirth leads to evolution and expression of proteins in the brains of newborns that improve brain development and function in adulthood, according to research from the Medical School of Yale University in the USA.
Translation: Stelios Papaventsis Pediatrician, MRCPCH, DCH, IBCLC | www.pediatros-thes.gr Their research also shows that children churrascos born by Caesarean section have reduced expression of this protein in their brains. The research was published in August 2012 in the journal PloS ONE and conducted by researchers at the Department of Biomedicine. The research team studied the effects churrascos of childbirth and surgery birth to a mitochondrial protein, UCP2 in mice. This protein is essential for the proper development of neuronal circuits churrascos in the brain area called the hippocampus. The protein helps protect nerve cells in their growth and increase of synapses - the connections between cells. The hippocampus is responsible for short and long memory. The same protein UCP2 is involved in cellular metabolism of fat, and because the fat is an important component of breast milk, is likely to increase the composition of the normal vaginal delivery to assist in the transition to breastfeeding. The researchers found that the protein expression was increased in the hippocampus in neonates born by vaginal delivery, churrascos and was significantly suppressed in those delivered churrascos by caesarean section. The suspension of the operation resulted in reduced number and growth of nerve cells in the region churrascos and reduced synaptogenesis. They also found that the behaviors of adult mice after caesarean were problematic in relation to the operation of the hippocampus, which means that the UCP2 gene suppression or inactivation of the protein function churrascos inhibited the differentiation of neurons and neural circuits in the brain. Protein expression is promoted in conditions churrascos of stress, hypoxia or ischemia. Vaginal birth is this normal stress provided by nature. Conversely, the absence of stress elective cesarean section may lead to reduced expression of this protein churrascos in the newborn. These researchers conclude that the UCP2 protein can potentially play a crucial role in the proper churrascos development of brain circuits and associated behaviors. The increasing incidence of caesarean sections that are motivated by needs other than medical indications (convenience) can result in a permanent negative effect on brain development and function in humans. Source: Simon-Areces J, Dietrich MO, Hermes G, Garcia-Segura LM, Arevalo MA, et al. (2012) Ucp2 Induced by Natural Birth Regulates Neuronal Differentiation of the Hippocampus and Related Adult Behavior. PLoS ONE 7 (8): e42911. doi: 10.1371/journal.pone.0042911
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